Season 12 of The Big Bang Theory is set to be last run of the CBS sitcom with the show debuting tonight (Monday, September 24) in America.
The series is then expected to be hitting UK screens on Channel 4’s E4 a couple of weeks later.
Episodes will be airing on a weekly basis with a total of 24 instalments to keep fans happy.
The Big Bang Theory season 12 will be picking up from the events of the last run, but what happened last year?
What happened in The Big Bang Theory season 11?
Sheldon & Amy get married
Season 11 was a huge one for The Big Bang Theory with Amy Farrah Fowler (played by Mayim Bialik) and getting ready to tie the knot.
Most of the season saw Sheldon and Amy planning their upcoming nuptials with varying degrees of success.
One episode focused on Sheldon reconciling with his brother George (Jerry O’Connell), who was the one left looking after the family when he went off to college.
George initially refused to attend the wedding but after a heart-to-heart the brothers finally reconnected.
Sheldon also got some help from his friend Professor Stephen Hawking to get to his big day.
They finally ended up getting married with Star Wars actor Mark Hamill serving as the officiant.
Howard & Bernadette have a baby
The show also saw Bernadette Rostenkowski-Wolowitz (Melissa Rauch) and Howard Wolowitz (Simon Helberg) discovering that they were expecting another baby.
After finding out he was going to become a father, Howard is left full of doubts and goes to Sheldon for help with limited success.
They named their child Michael after much disagreement between the couple.
Sheldon tries to become an actor
Sheldon tried and failed to become an actor after auditioning for a role in a reboot of his favourite TV show as a child: Professor Proton.
He went to Star Trek actor Wil Wheaton for advice on acting but failed to get the role. Instead, Wil gets the part – much to Sheldon’s annoyance.
Penny & Leonard
Penny (Kaley Cuoco) and Leonard Hofstadter (Jonny Galecki) were named maid of honour and best man to Amy and Sheldon respectively.
The couple also vowed to do more things together before they had children.
Raj & Ruchi
Raj Koothrappali (Kunal Nayyar) embarked on a romance with Ruchi (Swati Kapila) but things didn’t go quite to plan when she insisted she just wanted to keep things causal.
To make things more complicated, Bernadette asked Raj to spy on Ruchi because she was convinced she was stealing her project work.
Bernadette was right and Ruchi was stealing from her but Raj defends his beau.
When Ruchi found out that Raj had been spying on her for Bernadette, she dumped him and he was single once more.
He had less luck when he started dating a separated woman called Nell (Beth Behrs), who also worked at the Planetarium with him.
But it didn’t end well when her husband Oliver (Walton Goggins) finds out and corners them.
Young Sheldon season 1 and The Big Bang Theory season 11 are available on Blu-Ray & DVD now
The Big Bang Theory season 12 airs on CBS in America tonight and will air on E4 in the UK later this year