Monkeypox was contracted by one person in Blackpool on Wednesday, September 26, in the first transmitted case in UK borders.
The disease was caught by a healthcare worker looking after a patient who had caught the disease before.
Both patients are now being treated at Blackpool Victoria Hospital for the disease, while the third resides in London Free hospital.
Monkeypox exists between chickenpox and Smallpox in terms of severity and can present as quite a gruesome disease.
What is Monkeypox?
Monkeypox is traditionally a zoonotic (animal) infection spread to humans via contact with infected animals.
Normally, the disease originates in the eastern and central portions of continental Africa, specifically in Nigeria.
Monkeypox is endemic in these areas and spread in countries outside of the region can usually be traced back there.
However, once someone has contracted Monkeypox, transmission between humans can take place.
Human-to-human transmission is a factor in Monkeypox, which can spread similarly (but not quite as potently) to the flu.
The infection is spread via droplets, which refers to contact with an infected persons bodily fluids.
In people, this can be done via sneezing, contaminated objects or surfaces and contact with skin lesions.
Any outbreak of Monkeypox means public notification is mandatory, and health organisations recommend further infection control precautions.
What are the symptoms of Monkeypox?
Monkeypox symptoms generally mirror those of Smallpox, with a characteristic widespread rash.
The infection has an incubation period of roughly 5-21 days, and initial symptoms present similarly to the flu.
A fever (temperature more than 38C) and intense headache start off the infection, after which lymph nodes swell in a condition named lymphadenopathy.
After this, people will start to feel weak and tired before they start to break out in a rash.
The Monkeypox rash starts to appear from one to three days into infection, initially as flat skin lesions named maculopapules.
These then become a raised rash named vesicles before growing outwards as pustules, large pus-filled lumps.
After pustules form, they generally stick around for less than three weeks, but are prone to scabbing and crusting.
The rash will start to drop off the skin when the disease has run its course.
Monkeypox has a fatality rate from one to 10 percent and management is supportive due to lack of available treatment.