Le Carre, 86, will play a waiter in the adaptation of his 1983 book The Little Drummer Girl.
It is described as a “blink-andyou-miss-it part” but eagle-eyed viewers will spot his bushy eyebrows and shock of white hair.
Le Carre – real name David Cornwell – spent much of his early writing career out of the spotlight. But he occasionally slips himself into screen versions of his books.
In the BBC’s 2016 adaptation of his book The Night Manager he played a disgruntled diner who finds himself caught up in a restaurant punch-up.
The drama’s star Tom Hiddleston later said that Le Carre refused to stick to the script and improvised his lines Le Carre’s son Stephen Cornwell, who produced the BBC series, said that his father was “not always the most patient” and thought the dialogue needed improving.
The novelist also had a silent cameo role in the 2011 film of his classic Tinker Tailor Soldier Spy, standing next to an agent dressed as Lenin at an MI6 party.
Tinker Tailor Soldier Spy, published in 1974, follows aging spymaster George Smiley in his bid to uncover a Soviet mole at the heart of the British Secret Intelligence Service.
It remains a staple of spy fiction. The earliest known Le Carre cameo appearance was in a 1984 US film version of The Little Drummer Girl. His latest scene is understood to have been filmed in the Czech Republic.
Set in the late 1970s, The Little Drummer Girl weaves a story of international intrigue, love and betrayal, say its producers.
The new BBC adaptation will be on screen later this year. Le Carre worked for British intelligence in the 1950s and 1960s.
He went on to write full-time. His best-selling novels also include The Spy Who Came In From The Cold and Smiley’s People.
The master of espionage is not the first top writer to step out from shadow. Alfred Hitchcock had cameos in more than 35 of his films.
He was frequently carrying a musical instrument.
Edward St Aubyn was a notoriously private novelist but made a cameo appearance in the recent Sky TV adaptation of his Patrick Melrose novels.
Michael Morpurgo made a cameo appearance in the Broadway production of his novel War Horse. The former children’s laureate was in crowd watching an auction during a 2011 matinee.