The Southhampton-based cruise line is launching a series of short breaks and week-long journeys onboard the flagship Britannia ship and new vessel Iona.
However, passengers will only be welcomed onboard if they can prove they have received both of their COVID-19 vaccinations.
Travel insurance will also be mandatory for guests.
Cruises will depart from Southampton between June and September, with the aim of seeking out the spots of the British Isles where “the sun shines brightest”.
P&O Cruises president Paul Ludlow said: “Given recent announcements, we have every hope that our guests will be able to enjoy a holiday this summer.
“After the stresses and challenges of the past year, everyone certainly deserves a treat and this series of cruises will provide memorable and much needed UK getaways.
“Whilst there is still uncertainty about holidays abroad this summer, we are delighted to be able to offer our guests the ultimate escape here in the UK with the reassurance that we will take care of everything.
“Also, we really will look at the weather forecast for each cruise and aim to take our ships where it is warm and sunny.
“As the start of Iona’s very special maiden season, the new Ultimate Escape series of holidays includes a memorable seven-night maiden voyage sailing around the Scottish islands.
“Iona will anchor off Iona, the island after which she was named, with a celebratory extended stay until sunset for magical views of the historic shores.”
Prices start from £449 per person for a three-night break on Britannia.
Iona’s seven-night maiden voyage starts from £1,199 per person.
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The cruises will be scenic-only and take in the views of the British Isles and surrounding islands.
The line’s newest ship Borealis will be the first to embark on such a journey, travelling on a three-night voyage from Liverpool on July 5.
Bolette will depart on a three-night journey from Dover on August 16.
Other routes will include the Shetland and Orkney Islands, and the Isles of Scilly.
Peter Deer, managing director at Fred. Olsen Cruise Lines, said: “We are so excited to be unveiling these new summer cruises.
“So often overlooked, our British Isles are home to some of the most wonderful wildlife, and so much spectacular scenery that is best enjoyed from the water.
“With this selection of shorter sailings, guests can dip their toes back into cruising and enjoy all that they love about being on board with us, before we all begin to venture further afield again.”
“With the UK Government confirming that domestic travel is close on the horizon, we are introducing a series of exciting, shorter duration holidays for British residents looking for the perfect staycation in Cunard luxury this summer,” said Simon Palethorpe, president, Cunard.
“These will be sailings from Southampton, for UK residents, around the UK and will make the very most of the summer sunshine.”
More details on the UK itineraries are anticipated in the coming weeks.
However, so far when the holidays will go ahead and where they will span remain a mystery.
Posting to its Facebook page, the cruise line said: “We’re really pleased to announce we’ll be offering domestic cruises sailing from the UK this year.
“We can’t wait to welcome you back onboard. More details will be revealed soon.”
The 14 cruises will be available to vaccinated UK resident only and will depart from July 31.
The scheduled cruises are expected to last until the end of September onboard the Regal Princess and Sky Princess.
Cruises will depart from Southampton, with a range of three- and seven-night voyages.
Stops along the way include Liverpool, Belfast and Glasgow.
The three sailings will venture along the coast of England on a roundtrip from Portsmouth.
Sailings will depart on May 22, May 29 and June 5.
- ^ Cruise (www.express.co.uk)
- ^ travel (www.express.co.uk)
- ^ P&O Cruises (www.express.co.uk)
- ^ Camping & caravan: Expert shares luxury add-ons to boost holidays (www.express.co.uk)
- ^ Google Maps Street View: Aftermath of car accident spotted (www.express.co.uk)
- ^ Spain number one location for British expats data reveals (www.express.co.uk)
- ^ Fred Olsen (www.express.co.uk)
- ^ Cunard (www.express.co.uk)
- ^ Marella (www.express.co.uk)
- ^ Princess Cruises (www.express.co.uk)
- ^ Viking (www.express.co.uk)