Among patients who received two doses of the vaccine, the South African variant’s prevalence rate was eight times higher than those unvaccinated.
This indicates the Pfizer vaccine is much less effective against the South African mutation, compared to the original coronavirus strain and the variants first identified in Kent, the researchers explained.
Adi Stern, of Tel Aviv University, said: “We found a disproportionately higher rate of the South African variant among people vaccinated with a second dose, compared to the unvaccinated group.
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In Pfizer’s study of the South African strain, it said out of a group of 800 volunteers in South Africa, nine infections were found, all of which occurred among participants who got the placebo.
Of the nine cases, six were among individuals infected with the South African variant.
According to Stern, low prevalence of the South African strain was encouraging.
The government first announced it had detected two cases of the South African variant in the UK on 23 December 2020.
Up to 31 March, the number of cases had risen to 469.
Protection against the South African Variant with the AstraZeneca vaccine has also shown some concern.
The trial evaluated the safety and the efficacy of the AstraZeneca vaccine in HIV-negative adults aged between 18 to 64 years old with a median age of 30 years old.
Out of the trial’s 750 vaccine recipients, 19 developed mild to moderate COVID-19 more than 14 days after the second dose, compared with 23 of 717 placebo recipients.
Of the 42 total cases of COVID-19, 39 were caused by the South African variant.
There have now been more than 470 cases of the South African variant.
At the end of February there were fewer than 100 cases of the Nigerian variant, but in the last week this has climbed above 300.
While figures are still in the hundreds, and outweighed by the dominant Kent variant, experts are concerned as more people get vaccinated, the South African and Nigerian strains will spread more widely as the virus tries to escape the immunity created by the jabs.
A senior Sage source told The i: “If it can infect and transmit in vaccinated people, B1351 (South African variant) will increase in that population. It is slowly going up, but that might be because we are looking for it so hard.”