And with City pressing hard for an equaliser, you just wondered whether this was going to be their night after De Bruyne hit the deck.
As he tried to make a run off the ball, Rudiger stopped him in his tracks.
In doing so, both players fell to the deck in what looked a nasty collision in real-time.
BT Sport commentator Darren Fletcher feared the playmaker may have suffered a neck injury.
But those fears are eventually eased when De Bruyne rose to his feet, albeit gingerly.
The damage to De Bruyne’s eye was immediate as the bruising and swelling ballooned.
De Bruyne was then checked over by UEFA’s medical staff and was clearly devastated that his night ended early.
Five minutes later, he was spotted seated on the bench applying ice to the injury as he nervously watched on from the sidelines.
As Chelsea made a substitute on 80 minutes, De Bruyne was then pictured limping down the tunnel under the assistance of the City medical staff.
The scenes were reminiscent of the 2018 Champions League final, when Mohamed Salah’s night ended in Kiev for Liverpool.
Salah fell awkwardly in a tussle with Sergio Ramos before suffering a shoulder injury.
He would later be declared fit for the World Cup despite missing the first match for his country in Russia.
This post originally appeared on Daily Express :: Sport Feed