Michael will be replaced by former Blue Peter presenter Radzi Chinyanganya, 32, after the news was announced on Wednesday.
On having to withdraw from the show, the comedian said: “I am absolutely devastated; I have loved every second of the journey so far with my wonderful dance partner Alex Murphy and the support from the public has been overwhelming.
“I have been fortunate enough to work with such a great bunch of people over the previous few months; trainers, celebrities, pro skaters, the judges, Holly and Phil and the incredible production team at ITV who really are exceptional and help to make it the fantastic show that it is.”
With the Christmas special having been filmed in advance, Michael will still be included in the one-off show.
Dancing On Ice returns Sunday, January 5, 2020, on ITV.