NASA news: 'Mighty mice' return from ISS to Earth in bid to ‘enhance health’ of astronauts

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NASA news: 'Mighty mice' return from ISS to Earth in bid to ‘enhance health’ of astronauts 1

The record-breaking rodents dubbed “mighty mice” splashed down in a SpaceX Dragon capsule in the Pacific Ocean this time last week. The mice, provided by the nonprofit Jackson Laboratory in Maine, were genetically modified for muscle growth in an experiment to better understand how zero gravity affects the human body.

Astronauts on long-term spaceflight missions experience muscle and bone loss.

Although this atrophy can be mitigated with exercise, experiments like this can help experts understand how the loss occurs and to better manage it.

These mice are just one of many groups of rodents sent to the orbiting space station over the years in the name of research.

The mice began their stay on the space station after docking on December 8.

The experiment was called Rodent Research-19 and it was used to study both myostatin and activin, the molecular signalling pathways able to influence muscle degradation, according to the US space agency NASA.

Researchers believe these pathways could be targets to prevent muscle and bone loss during missions and help with recovery efforts once astronauts return to Earth.

As is often the case with space station experiments, the findings could also help develop therapies for those dealing with muscle and bone loss due to various conditions on Earth.

This includes muscular dystrophy, osteoporosis and diseases that cause muscle wasting like cancer, heart disease, sepsis and even AIDS.


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