Chris Bosh’s playing career ended years before he planned. Jay Wright was in trouble three years into a tenure at Villanova. Chris Webber was a finalist for years.
This post originally appeared on CBS8 – Sports
Chris Bosh’s playing career ended years before he planned. Jay Wright was in trouble three years into a tenure at Villanova. Chris Webber was a finalist for years.
This post originally appeared on CBS8 – Sports
This has caused some difficulties for those looking to acquire visas, as well as Britons already living in the EU who may have been forced to return home.
According to the data, 12,715 households relocated to the UK over the past year.
The report states: “The origin countries for relocations to the UK are all expat hotspots including USA, Australia, Canada and Spain, suggesting people are giving up their international dreams to be closer to family.”
The top eight countries from where UK arrivals departed include the USA, Australia, Canada, Spain, France, Germany, Ireland and New Zealand.
This post originally appeared on Daily Express :: Travel Feed
About 2% of asymptomatic college students carried 90% of COVID-19 viral load levels on a Colorado campus last year, new research reveals. Furthermore, the viral loads in these students were as elevated as those seen in hospitalized patients.
“College campuses were one of the few places where people without any symptoms or suspicions of exposure were being screened for the virus. This allowed us to make some powerful comparisons between symptomatic vs healthy carriers of the virus,” senior study author Sara Sawyer, PhD, professor of virology at the University of Colorado Boulder, told Medscape Medical News.
“It turns out, walking around a college campus can be as dangerous as walking through a COVID ward in the hospital, in that you will experience these viral ‘super carriers’ equally in both settings,” she said.
“This is an important study in advancing our understanding of how SARS-CoV-2 is distributed in the population,” Thomas Giordano, MD, MPH, professor and section chief of infectious diseases at Baylor College of Medicine in Houston, told Medscape Medical News when asked to comment on the research.
The study “adds to the evidence that viral load is not too tightly correlated with symptoms.” In fact, Giordano added, “This study suggests viral load is not at all correlated with symptoms.”
Viral load may not be correlated with transmissibility either, said Raphael Viscidi, MD, when asked to comment. “This is not a transmissibility study. They did not show that viral load is the factor related to transmission.”
“It’s true that 2% of the population they studied carried 90% of the virus, but it does not establish any biological importance to that 2%,” added Viscidi, professor of pediatrics and oncology at the Johns Hopkins University School of Medicine, Baltimore, Maryland.
The 2% could just be the upper tail end of a normal bell-shaped distribution curve, Viscidi said, or there could be something biologically unique about that group. But the study does not make that distinction, he said.
The study was published online May 10 in PNAS, the official journal of the National Academy of Sciences.
Out of more than 72,500 saliva samples taken during COVID-19 screening at the University of Colorado Boulder between August 27 and December 11 of last year, 1405 were positive for SARS-CoV-2.
The investigators also compared viral loads from students to those of hospitalized patients based on published data. They found the distribution of viral loads between these groups “indistinguishable.”
“Strikingly, these datasets demonstrate dramatic differences in viral levels between individuals, with a very small minority of the infected individuals harboring the vast majority of the infectious virions,” the researchers write. The comparison “really represents two extremes: One group is mostly hospitalized, while the other group represents a mostly young and healthy (but infected) college population.”
“It would be interesting to adjust public health recommendations based on a person’s viral load,” Giordano said. “One could speculate that a person with a very high viral load could be isolated longer or more thoroughly, while someone with a very low viral load could be minimally isolated.
“This is speculation, and more data are needed to test this concept,” he added. Also, quantitative viral load testing would need to be standardized before it could be used to guide such decision making
It should be noted that the research was conducted in fall 2020, before access to COVID-19 immunization.
“The study was performed prior to vaccine availability in a cohort of young people. It adds further data to support prior observations that the majority of infections are spread by a much smaller group of individuals,” David Hirschwerk, MD, told Medscape Medical News when asked to comment.
“Now that vaccines are available, I think it is very likely that a repeat study of this type would show diminished transmission from vaccinated people who were infected yet asymptomatic,” added Hirschwerk, an infectious disease specialist at Northwell Health in New Hyde Park, New York, who was not affiliated with the research.
“This finding has been in the literature in piecemeal fashion since the beginning of the pandemic,” Sawyer said. “I just think we were the first to realize the bigger implications of these plots of viral load that we have all been seeing over and over again.”
How a minority of people walk around asymptomatic with a majority of virus remains unanswered. Are there special people who can harbor these extremely high viral loads? Or do many infected individuals experience a short period of time when they carry such elevated levels?
The highest observed viral load in the current study was more than 6 trillion virions per mL. “It is remarkable to consider that this individual was on campus and reported no symptoms at our testing site,” the researchers write.
In contrast, the lowest viral load detected was 8 virions per mL.
Although more research is needed, the investigators note that “a strong implication is that these individuals who are viral ‘super carriers’ may also be ‘super-spreaders.’ ”
Some of the study authors have financial ties to companies that offer commercial SARS-CoV-2 testing, including Darwin Biosciences, TUMI Genomics, Faze Medicines, and Arpeggio Biosciences.
PNAS. Published online May 10, 2020. Full text
Damian McNamara is a staff journalist based in Miami. He covers a wide range of medical specialties, including infectious diseases, gastroenterology and critical care. Follow Damian on Twitter: @MedReporter.
This post originally appeared on Medscape Medical News Headlines
Chest pain is one of the alarm signals of a heart attack which can last a few minutes or longer. Typically, the pain feels like a heavy weight on the chest or like squeezing in the chest. However, there can be more subtle symptoms which could indicate a silent heart attack. What are the main differences between the two?
A silent heart attack is a heart attack that has few, if any, symptoms or has symptoms you don’t recognise as a sign of a heart attack.
A person might not have chest pain or shortness of breath, which are typically associated with a heart attack.
Most people don’t realise that they could have a heart attack without even knowing it.
Although these are commonly referred to as “silent” heart attacks, a more accurate term may be “unrecognised” heart attack.
Some people do have symptoms, so in that sense, their heart attack is not silent, said Dr David Morrow, director of the cardiac intensive care unit at Harvard-affiliated Brigham and Women’s Hospital.
He continued: “They just don’t recognise the sensations as coming from their heart.
“They may think it’s just indigestion or muscle pain, when the real cause is actually reduced blood flow to the heart.
“People may also experience other atypical symptoms, such as nausea or excessive sweating during a heart attack.”
During a heart attack, the duration and intensity of symptoms can vary quite a bit.
In general, there must be 15 to 30 minutes of reduced blood flow to result in a detectable heart attack meaning a part of the heart muscle has become damaged or has died.
But sometimes symptoms come and go, and these are known as stuttering symptoms.
Some people have mild symptoms from a very large heart attack, while others have severe symptoms with a small heart attack.
This post originally appeared on Daily Express :: Health Feed
“What did Jack Whitehall say that got censored?” one person wrote.
While another said, “I’m really intrigued to see what Jack Whitehall said now, the fact is was muted.”
Someone else added: “What did @jackwhitehall say at the #BRITs? Any lip readers about?”
There were 4,000 people in the audience who didn’t need to wear masks or be socially distanced.
Over half of the tickets were given to key workers from London “to thank them for their remarkable hard work and selfless commitment” during the pandemic.
This post originally appeared on Daily Express :: Celebrity News Feed
The cast of Gogglebox have been “ranked” by viewers from “least to most popular”.
But the result is proving to be pretty controversial, with some fans taking issue with the judgements.
Eleven families were ranked by viewers of the sofa favourite, according to Birmingham Live.
The popular show airs each Friday night on Channel 4 at 9pm and features Hull’s very own Jenny and Lee.
Now, it is worth noting, before we continue, that only 11 families were ranked. So if your favourite is a secondary cast member who does not feature regularly, they may not appear below.
It is also worth noting this is not the opinion of Birmingham Live or Hull Live, but instead, based on votes from viewers who regularly tune in.
To sign up for the Hull Live newsletter, click here.
Here’s the list from least to most popular:
11. The Vens
Mica, boyfriend Marcus and her two daughters Sachelle and Shuggy first joined the show in 2018.
The south Londoners joined Gogglebox in series 11 and were ranked last in the vote last year, but we reckon they’ve surely jumped a few places this season.
The pair feature regularly – and have us chuckling with their brilliant chemistry.
10. The Michaels
Controversially to some, the Brighton family ranked higher than Mica and Marcus.
The Michael family had a brief break during their stint on the show but are now back all together.
Dad Andrew, mum Carolyne and son Louis are among the family members to feature.
Louis’ sister Alex appeared as well, as has her twin Catheryne.
9. Stephen Webb
Stephen Webb has featured alongside his husband Daniel, his former flatmate Chris and his mum ever since series one.
He is the longest serving cast member.
Recently, he thrilled people with his dramatic new hairstyle.
And he also birthed the meme ‘yeah, but not a terrorist, Chris’.
8. Dave and Shirley
Ah, the Welsh couple have stolen our hearts ever since their debut.
Welsh couple Dave and Shirley have been married for 40 years and have two children together.
They joined the show in 2015.
7. Ellie and Izzy
This is massively controversial according to BirminghamLive.
They are a popular pair and regularly amuse viewers with their back and forth banter and obsession with food.
They both have thousands of followers on social media.
But the pair only rank seventh.
6. Mary and Marina
OAPs Mary and Marina are both in their 80s and live in a retirement home together in Bristol.
They have become popular for their sense of humour and frank comments about men and relationships, while often getting distracted talking about their love lives.
5. The Siddiquis
The East Midlands family are brilliant – and their chemistry is undeniable.
The close knit family always entertain us with their brilliant takes.
4. The Malones
The Malone family have lost a member for the current series, with Tom Jr stepping away.
But that has not stopped them regularly featuring.
Since joining the show back in series four, the Malone family are known for blunt, no-nonsense remarks, enviable snack selection and their adorable dogs who aren’t camera shy.
3. Giles and Mary
Giles and Mary – or ‘Nutty’, as her husband calls her – are well known in the Gogglebox fan circles.
The couple’s home and sense of style is instantly recognisable, particularly Mary’s botanical armchair which matches the wallpaper.
2. Pete and Sophie
We expected Pete and Sophie to finish first and second – and so it proved.
The Blackpool duo are a close knit pair of siblings, with Sophie losing her job last year and being supported by viewers.
Pete, meanwhile, is set to get married and become a dad.
The duo are the envy of the nation with their mug collection.
1. Jenny and Lee
Jenny’s AC12 notes during Line of Duty won the hearts of the nation – and were enough to seal first spot.
The pals met in a pub where Jenny was the landlady and Lee was a regular.
They share a Twitter account which has amassed more than 129,000 followers and shows the comical friends sharing their exploits outside of filming.
*Gogglebox airs on Channel 4 at 9pm
Author: Patrick Svitek
This post originally appeared on The Texas Tribune: Main Feed
This post originally appeared on Stock Market News
By Carl O’Donnell and Julie Steenhuysen
(Reuters) – A U.S. plant that was making Johnson & Johnson (NYSE:)’s COVID-19 vaccine must fix a long list of problems including peeling paint, shoddy cleanups, and poorly-trained staff to resume operation, according to a highly critical report by the Food and Drug Administration.
Experts said addressing the issues raised in the scathing FDA inspection report could take months.
Neither J&J nor the FDA has said when they expect vaccine production to resume at the Baltimore plant owned by Emergent Biosolutions (NYSE:) Inc. Only one plant, in the Netherlands, is currently producing the key drug substance used in J&J’s vaccine, the company said.
“It may take many months to make these changes,” said Prashant Yadav, a global healthcare supply-chain expert at the Center for Global Development. He described some of the issues raised by the FDA as “quite significant.”
J&J said it would ensure that all of the FDA issues are addressed promptly and comprehensively.
The 12-page report described dirty facilities and many instances of potential contamination. In some cases, employees carrying unsealed medical waste collided with containers used to make material for vaccines, it noted, adding that containers had been spotted elsewhere with cracks.
Problems were not investigated and cleanups were superficial, it added. In one example, a worker moved between rooms where different materials were being made on 19 different days while only documenting a single required shower, the report said.
FDA inspectors said the facility was not large enough, describing crowded rooms difficult to walk through without bumping into containers of materials and small doors that forced workers to push containers on the ground rather than use machines to carry them.
“Paint flecks were observed on the floor all along the sides of these walls” on corridors surrounding the manufacturing room and in a room were vials were filled, it said in one section, adding that there was “brown residue” on the wall and “black residue” on the floor in one plant room.
The investigation confirmed media reports that J&J shots made at the Emergent plant had been contaminated with material used to make vaccine for AstraZeneca (NASDAQ:). At the time, workers responded to the mix up with little more than a routine cleaning, it noted.
Millions of J&J doses were ruined, the New York Times reported. Production of AstraZeneca’s vaccine was moved elsewhere.
“There is no assurance that other batches have not been subject to cross-contamination,” the report said.
J&J has drawn scrutiny for months over its halting process to scale up production of the one-shot vaccine that is easier to handle and use than other authorized vaccines.
Its use in the United States has been paused since last week as health officials study a possible link to a very rare but serious blood clot condition.
Emergent has been seeking regulatory authorization to make the J&J vaccine in the United States. It stopped production at the plant recently, saying the FDA had asked it to do so after an inspection.
“What’s important is that the FDA caught these deficiencies” and took steps to ensure the vaccine produced there was not used, said vaccine researcher Dr. Anna Durbin of Johns Hopkins University in Baltimore.
“Emergent has some work to do to clean up their process. They will likely need to be re-inspected by the FDA before any vaccine produced there would be accepted,” she said.
Johnson & Johnson reiterated on Wednesday that it was working to establish a global supply chain in which 10 manufacturing sites would be involved in production of its COVID-19 vaccine, in addition the Netherlands plant.
The company has a U.S. government-brokered agreement with rival drugmaker Merck & Co, which is preparing to make doses of J&J’s vaccine.
FAILURE TO TRAIN PERSONNEL
The inspection report said the FDA team had reviewed security camera footage in addition to an in-person site visit to the Emergent plant.
It found failure to train personnel to avoid cross contamination of COVID-19 vaccines from Johnson & Johnson and AstraZeneca.
Earlier this week, the U.S. House Representatives launched an investigation into whether Emergent used its relationship with a Trump administration official to get a vaccine manufacturing contract despite a record of not delivering on contracts.
Emergent said in a statement that it is working with the FDA and J&J to quickly resolve the issues outlined in the report.
The inspection, carried out between April 12 and April 20, also noted that Emergent did not produce adequate reports showing that the vaccines it was producing met quality standards.
J&J said it was redoubling its efforts to get authorization for the facility as quickly as possible.
J&J’s oversight could help Emergent better address the FDA’s concerns, none of which are especially difficult to fix, Cantor Fitzgerald analyst Brandon Folkes said in a note.
No vaccine manufactured at the Baltimore plant has been distributed for use in the United States.
This post originally appeared on RT Sport News
As football fans rejoice at toppling the European Super League, they must remain on their guard against the unfettered avarice that infests the boardrooms of those who plotted the ill-fated project.
Over in Spain, Real Madrid president Florentino Perez – the beleaguered Super League chairman – sifted through the ruins of a project he had disingenuously proclaimed to be ‘the saviour of football’. Barely 48 hours after it had entered the world, Perez was left cradling his stillborn with little hope of breathing life back into the project.
This was a spectacularly brazen power-grab from Europe’s Dirty Dozen, brought crashing down by myriad forces: from the supporters on the streets to the keyboard warriors on social media; from the TV diatribes by Gary Neville to the misgivings by Manchester City manager Pep Guardiola; from the open recalcitrance of Liverpool’s Jordan Henderson to the more subtle swipe from Manchester United’s Marcus Rashford. All played a part, and it all proved too much to stomach for bosses at Manchester City and Chelsea as they precipitated the English exodus.
As fiercely tribal as football is, this was a rare moment of solidarity when fans of all stripes could rejoice and revel in the feeling that – so often scorned – they had actually made a difference.
Also on rt.com ‘We saved football’: Chelsea go from villains to heroes as Abramovich set to pull team out of Super League (VIDEO)
The Super League was a project so incredibly ill-conceived that it begs the question: what were those behind it thinking? Why now, and why with such scant regard for the forces underpinning the game? Could they really have been so amateurish and out of touch as to fail to anticipate the fire and fury that would follow?
Rather than failing to read the room, they hadn’t even even bothered to enter it in the first place. Managers were hung out to dry while owners hunkered down, in keeping with how many of these distant billionaires have run their clubs since getting their hands on them.
The main motivation behind the Super League rebels was blindingly obvious: greed.
A superiority complex at the top of the game and the long-harboured feeling that the rich were not getting their fair share. The US influence was evident through the Glazers at Manchester United, Stan Kroenke at Arsenal and John W Henry at Liverpool. These are men used to operating in closed shops, where ‘equality’ exists but only among the established elite. The concepts of the footballing pyramid – promotion, relegation, the wild ebb and flow of fortunes – are alien to these men. They want franchises, and to hell with the rest.
The Super League plot planned to lock in their superiority in perpetuity. For all the talk of ‘solidarity payments’ for teams lower down the pyramid, this scheme would mean everyone outside the 15 permanent Super League clubs would be left feeding off scraps.
Also on rt.com ‘SPITTING in the face of fans’: UEFA chief blasts ‘self-serving’ Super League rebels, says players will be BANNED if taking part
The malign American influence is not the only explanation for this malfeasance, however. Real Madrid’s Perez was a very public driving force, as was Juventus chairman Andrea Agnelli. Both are businessmen but could also – in the loosest sense – be deemed ‘football men’. The Agnelli family have owned Juve since 1923; Perez has been Real Madrid president for the better part of two decades.
It is Perez who has been the bumbling face of the Super League, with his claims that youngsters no longer cared about football, that matches needed to be shorter, that the whole system needed overhauling. ‘I’ll bring you modernity’, was the message from the 74-year-old billionaire supposedly with his finger on football’s pulse.
In reality, Real Madrid and co-conspirators Barcelona are in financial dire straits, desperate for funds having spectacularly mismanaged their books. Their salvation was to be found in gorging themselves even more on the riches brought about by the Super League.
Some have pondered whether all this was just a big ruse to force UEFA into yet more reforms, handing the biggest teams more power and a bigger slice of the pie. The timing and nature of this whole shambles suggests that was not the case. The likes of Agnelli and now-departed Man Utd vice-chairman Ed Woodward were negotiating reforms to the Champions League with UEFA while simultaneously cooking up their Super League plans.
UEFA defiantly pressed ahead with its announcement on Monday that its flagship tournament would implement changes from the 2024-25 season, which will see the Champions League expanded from 32 teams to 36, based on a new ‘Swiss model’. That move was seen as a concession to the bigger teams as it would hand them more games against their fellow elite.
That clearly wasn’t enough, though. A breakaway Super League has been years in the making, but its initiators felt now was the time to finally strike. The financial ravages of Covid-19 have hastened their move, but it was a step they were nonetheless well on the way to taking. This time they also had the billion-dollar finances in place through JP Morgan, although in keeping with their amateur hour antics, were without a broadcaster lined up.
Also on rt.com The European Super League was unfathomable to anyone with common sense – could it be the ultimate exercise in calling our bluffs?
By most accounts, Chelsea and Man City were reluctant to get onboard, but ultimately feared missing the boat. It was telling that they were the first two teams to abandon the sinking ship.
All of the Dirty Dozen will likely now have to return, heads bowed, back to UEFA. For all its faults – and they are myriad – UEFA has emerged looking like the good guy in all of this. It will sting for the likes of Perez and Agnelli to have to grovel on their way back, as seems inevitable.
There is hypocrisy each way you turn in this whole fiasco. In the UK, Sky Sports and BT have trumpeted their opposition to the Super League, giving a platform to the likes of Neville to hold forth on its ills, and yet both broadcasters continue to charge extortionate fees for the average football fan.
Paris Saint-Germain were held up as paragons of loyalty for refusing to turn their backs on UEFA, yet many pointed out their motives were likely just as much tied up in the vested broadcasting interests that PSG chairman Nasser Al-Khelaifi has in the Champions League as head of Qatari TV behemoth beIN Sports.
In some sections of the media, Manchester City owner Sheikh Mansour has been trumpeted for supposedly being the “unlikely saviour” of football. Given the reasons behind the Abu Dhabi takeover at the club, that is frankly laughable. City and Chelsea should both have a long, hard look at themselves for going along for the Super League ride in the first place.
Even the likes of Sir Alex Ferguson did not escape censure after criticizing the Super League plans, as it was swiftly pointed out that he had backed the Glazer family in their debt-laden takeover at Old Trafford.
There have been casualties. Ed Woodward is gone from Old Trafford, a move long overdue for most of the United faithful. Liverpool owner Henry issued a public apology on Wednesday, expressing his sadness for the “disruption” he has caused in recent days.
But as long as he feels the profits are there, Henry will stay on at Liverpool – just as Joel Glazer will at Manchester United, and Stan Kroenke will at Arsenal. Driven by their relentless pursuit of profits, these money men will come again with plans to restructure and reshape football, to the detriment of the fans and fellow teams who have helped build it into what it is.
Football will pat itself on the back for having staved off this crisis, but many more equalities and injustices remain. The threat of a European Super League still looms on the horizon, even if the current iteration has been vanquished.
“We shall reconsider the most appropriate steps to reshape the project,” read a statement from the league issued amid the rubble on Tuesday night.
Yes, they will have been burned by this experience, but football’s money men have not been defeated completely.
Football fans have won the battle, but the war against the game’s rapacious greed very much goes on.
By Liam Tyler
Elgin ISD Superintendent Dr. Jodi Duron said Alyssa Broderick and Willie Simmons III were killed Sunday and both were active in the district, both academically and athletically.
Duron said Broderick left the district in the fall, but was a student from 2009 to 2020.
“She was an excellent student and athlete, enrolled in our Early College High School program and played on our girls’ basketball team,” Duron said.
Simmons III was a captain of the high school football team and signed to play college football at the University of North Texas.
“He was an exceptional young man and leader among his peers,” Duron said. Simmons III was a National Honor Society member and he “represented the very best of Elgin ISD.”
“The Elgin ISD community grieves the loss of these two young, promising souls,” Duron said.
Grief counselors and other professionals are available for students, staff and family members to help them cope with the tragedy, Duron said.
Law enforcement has not confirmed the identity of the victims. While the suspect and one of the victims have the same last name, it’s still unclear if they are related.
Broderick was taken into custody by Travis County Sheriff’s Office deputies and Manor Police around 7:30 a.m Monday. Authorities said Broderick had a pistol tucked in the waistband of his pants when he was arrested but was compliant. He was found walking on Old Kimbro Road outside Manor, and authorities say 911 calls tipped them off to his location.
This article originally appeared on KXAN Austin