Tag Archives: pregnancy

FDA to Cut Broadly Worded Statin Pregnancy Contraindication

The US Food and Drug Administration (FDA) aims to update the labeling on all statins to remove the drugs’ blanket contraindication in all pregnant patients, the agency has announced. The change should reinforce for both physicians and patients that statin use in women with unrecognized pregnancy is unlikely to be harmful, it said.

“Because the benefits of statins may include prevention of serious or potentially fatal events in a small group of very high-risk pregnant patients, contraindicating these drugs in all pregnant women is not appropriate.”

The revision should emphasize for clinicians “that statins are safe to prescribe in patients who can become pregnant and help them reassure patients with unintended statin exposure in early pregnancy” the FDA explained.

Removal of the broadly worded contraindication should “enable health care professionals and patients to make individual decisions about benefit and risk, especially for those at very high risk of heart attack or stroke.” That includes women with homozygous familial hypercholesterolemia and those who are prescribed statins for secondary prevention, the agency said.

Clinicians “should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy. Because of the chronic nature of cardiovascular disease, treatment of hyperlipidemia is not generally necessary during pregnancy.”

Follow Steve Stiles on Twitter: @SteveStiles2. For more from theheart.org, follow us on Twitter and Facebook.

Read more
This post originally posted here Medscape Medical News

Janette Manrara's Strictly exit sparks pregnancy speculation from fans 'Must be a reason!'

She added on Instagram: “All our dreams can come true, if we have the courage to pursue them” -Walt Disney

“I am absolutely thrilled to be joining @rylan on #ItTakesTwo this series! A show where we can sit and talk about dancing?!? It’s the dream! I can never replace the legendary @zoetheball, but I can only hope to make her as well as all of the @bbcstrictly fans proud.

“My dance mentor and best friend @jasongilkison I will miss being a part of your creative journeys on the dance floor more than you can ever imagine. And to the everyone who works on #Strictly, from hair and make-up, wardrobe, cameras, the lot…. it’s not goodbye, it’s more “I’ll see you around” Thank you all for some of the most “fab-u-Lous” memories of my life!”

She added: “The hardest part will be saying goodbye to my fellow professional dancers and the famous Strictly dance floor! The professionals are the superheroes of the show and I will always champion them! I love you all so so much! May you continue inspiring and bringing so much joy to the nation as always!

“I am over the moon and cannot WAIT to get on that very special couch! And do not worry guys, I will always “keeeeeeeeeeeep dancing”! It Takes Two…… “baby!!”

This post originally appeared on Daily Express :: Celebrity News Feed

Ben Fogle 'confused' after wife sends pregnancy scan snap 'I've been away for a long time'

Countryfile presenter Ben Fogle, 47, has opened up about his “confusion” after his wife, Marina, sent him a snap of an ultrasound pregnancy scan. The TV host took to social media to celebrate the happy news, but revealed he was in shock as he has been away from home for “a long time”. However, in a turn of events, the star went on to reveal that the expectant mother wasn’t his wife.

Taking to Instagram, the BBC star shared the news with his 376,000 fans.

Ben posted a sweet snap of a black and white ultrasound scan, which he said his spouse had sent him.

He wrote: “Marina just sent me this with no words which got me reaaaaallllly confused…. because I’ve been away for a long time.”(sic)

The star went on to reveal that the expecting mother wasn’t the mother of his two children, but instead their dog, Nero, as he added: “#puppies.”

READ MORE: Paula Radcliffe talks feeling ‘guilty’ after daughter’s cancer news

In a post shared by his wife, Marina revealed that her beau had been away filming at Longleat Safari Park.

In a follow-up picture, the adventurer revealed that he had received “disgusted” messages from social media users about owning a pregnant dog.

Sharing a cute picture of his son Ludovic cuddling the family dog, Ben reassured fans that he and his father are not “puppy farmers”.

The star started by thanking fans for the “concerned” messages about their pregnant black Labrador, before admitting that the pregnancy was “carefully considered”.

He went on to emphasise how important puppies are when it comes to training them from an early age to become service dogs.

Ben added: “Those ‘disgusted’ that we have a pregnant dog might want to consider that charities like Hearing Dogs for Deaf people, co-founded by my father, rely on good, young dogs to train.”

He added: “I was sharing an amusing post about pregnancy and puppies.

“It’s the summer. The sun is shining. Love, peace and puppy licks,” he signed off.

This post originally appeared on Daily Express :: Celebrity News Feed

Vaping and Pregnancy: Inhaled Toxins Among Reasons for Pause

Researchers are trying to understand how e-cigarette use affects pregnancy and birth outcomes. This question may become more relevant as younger vapers, among whom the devices gained considerable popularity, start having children.

Limited emerging data from animal experiments and human epidemiologic studies suggest that vaping may have negative effects on fertility and pregnancy. “Even if these impacts are less severe than conventional smoking, we really should be thinking about alternate options that may be safer for our patients than inhalation of this aerosol,” said Blair J. Wylie, MD, MPH, a maternal-fetal medicine physician at Beth Israel Deaconess Medical Center in Boston.

Wylie reviewed what is known about vaping, including chemicals other than nicotine that have been detected in vape aerosols, and pregnancy at the 2021 virtual meeting of the American College of Obstetricians and Gynecologists.

“There’s a lot we don’t know,” she said. “These products were only introduced recently, in 2003. They are marketed aggressively to our youth and have gained tremendous popularity among that population. And it’s only a matter of time, I think, before we see a lot of use in our own patient population.”

In a separate study presented at the ACOG meeting, Nicole Izhakoff, a researcher at Florida International University, Miami, and colleagues evaluated the association between e-cigarette use during pregnancy and unfavorable birth outcomes, such as preterm birth, low birth weight, or extended hospital stay for the newborn.

The investigators used 2016-2017 survey data from the Pregnancy Risk Assessment Monitoring System. In all, 71,940 women completed the survey, including 859 who reported e-cigarette use during pregnancy.

After adjusting for age, race, ethnicity, insurance, maternal education, prenatal care, abuse during pregnancy, and complications during pregnancy, the researchers estimated that the odds of an unfavorable birth outcome were 62% greater among women who used e-cigarettes during pregnancy, compared with those who did not.

The researchers lacked information about simultaneous use of alcohol, traditional tobacco, or other drugs, however.

“Physicians of all subspecialties, especially those of obstetrics-gynecology and pediatrics, need to increase the implementation of screening for past or current e-cigarette use in at-risk patients,” Ms. Izhakoff and coauthors concluded. “Further research regarding the long-term health effects of e-cigarettes is warranted.”

Wylie coauthored another study related to this topic that was published online May 24, 2021, in the Journal of Maternal-Fetal & Neonatal Medicine.

The researchers examined birth weights of children whose mothers use e-cigarettes alone, those whose mothers used both e-cigarettes and conventional cigarettes, and those whose mothers smoked conventional cigarettes only. Their estimates were imprecise, but signaled that e-cigarette use may reduce birth weight. The use of e-cigarettes alone appeared to have less of an impact on birth weight than the dual use of conventional cigarettes and e-cigarettes did.

Wylie cautioned that outcomes like birth weight are “pretty crude measures of whether an exposure is okay or not in pregnancy. Many of these toxins that we know that are in the aerosols can cause harm, but they may not be reflected in the absolute value of the birth weight.”

In addition, clinicians should avoid focusing on the wrong question when caring for patients.

“I think the wrong question is: Is vaping safer than smoking?” Wylie said in an interview. “Metals are going into your lungs. Plastics are going into your lungs. It is hard for me to think that we are going to identify that as our champion smoking cessation strategy in pregnancy.”

Rapidly Changing Landscape

Answering the question of which is safer is a challenge anyway because researchers likely have incomplete information about who vapes, who smokes, and who does both.

Still, the new research illustrates that “people are starting to think about this and beginning to do some analysis that is really hypothesis generating at this point,” Wylie said. Such studies may prompt clinicians to ask their patients about e-cigarette use. “Marijuana is sort of a similar thing where patients’ perception of safety, because things are legal, can lead to use during pregnancy without … letting their care teams know,” she said. “Things are changing so rapidly in terms of what’s available to people to use that we need to stay on top of that as obstetricians and ask the right questions and try to understand what the risks are and potential benefits.”

Wylie is an obstetric consultant to the New England Pediatric Environmental Health Specialty Unit, which is where she heard pediatricians discussing widespread e-cigarette use among youth. It occurred to her that some of these teens eventually would be seeing obstetricians. She also saw parallels to prior research she conducted that focused on household air pollution or cooking from wood-burning fires in Africa.

“What is frightening, I think, about these electronic cigarettes is that you’re heating this liquid to extraordinarily high temperatures to create the vapor,” and the extreme heat vaporizes plastics and metals as well as nicotine, Wylie said.

An ACOG committee opinion discusses approaches to smoking and vaping cessation such as counseling, behavioral therapy, and medication.

The publication also lists a host of elements have been isolated from vape aerosol, including “carbonyl compounds (formaldehyde, acetaldehyde, acetone, and acrolein); volatile organic compounds (benzene and toluene); nitrosamines; particulate matter; and heavy metals such as copper, lead, zinc, and tin.”

In addition to the nicotine in e-cigarette liquids, which is harmful in itself, there is “all of this other company that it keeps,” including solvent byproducts, known carcinogens, and lung irritants, Wylie said. Fine particulate matter “can land in the small airways and cause inflammation, even translocate into the systemic circulation and cause systemic inflammation.”

The use of flavoring “likely alters perceptions of harm” and contributes to the popularity of vaping, Wylie noted. At the same time, the use of flavoring also has little regulatory oversight. Flavors usually are approved for marketing based on safety for ingestion, but that may not translate into safety for inhalation.

Parsing the Health Effects

People who vape have increased cough, wheezing, and phlegm production, compared with people who do not vape. Vaping also may worsen underlying lung disease like asthma. Lung function on spirometry decreases after e-cigarette use, studies have shown.

In 2019, researchers described e-cigarette or vaping product use–related acute lung injury (EVALI), which has caused more than 60 deaths in the United States. The condition may be related to vitamin E acetate, a component that had been used in some liquids used by patients with EVALI.

And the nicotine in e-cigarettes can accelerate atherogenesis and affect blood pressure, heart rate, and arterial stiffness.

Initially introduced as a smoking cessation tool, e-cigarettes now often are used on their own or in addition to cigarettes, rather than strictly for smoking cessation.

A Cochrane review suggests that e-cigarettes may be more effective than other approaches to smoking cessation. But “the effect is modest at best,” Wylie said. Among 100 people attempting to quit cigarette smoking, there might four to six more quitters with the use of e-cigarettes as a smoking cessation intervention, compared with other approaches.

Animal models provide other reasons for caution. One experiment in mice showed that exposure to e-cigarette aerosol impaired implantation and fetal health. The results suggest “that there might be some negative impacts across generations,” Wylie said.

Another study has suggested the possibility that women who currently use e-cigarettes may have slightly diminished fecundability. The results were not statistically significant, but the study “gives us pause about whether there could be some impact on early pregnancy and fertility,” Wylie said.

In mouse models, prenatal exposure to e-cigarette aerosol has decreased fetal weight and length, altered neurodevelopment and neuroregulatory gene expression, and increased proinflammatory cytokines. E-cigarette aerosol also has caused birth defects in zebrafish and facial clefting in frogs. Whether and how these data relate to human pregnancy is unclear.

While e-cigarette ads may convey a sense of style and harmlessness, clinicians have reasons to worry about the effects. “We have to be a little bit more cautious when we are talking about this with our patients,” Wylie said.

Wylie had no relevant financial disclosures. She is a Society for Maternal-Fetal Medicine board member and receives grant support related to research of household air pollution and pregnancy, prenatal pesticide exposure, preeclampsia in low income settings, and malaria during pregnancy. Ms. Izhakoff and coauthors had no disclosures.

This article originally appeared on MDedge.com, part of the Medscape Professional Network.

This post originally appeared on Medscape Medical News Headlines

Stacey Solomon: Loose Women star drops baby news in surprise pregnancy announcement

Stacey is planning to wed her partner Joe later this year after the pair shared their engagement news in December.

The couple welcomed their first child – Rex – in May 2019.

Stacey is already a mum to Zachary and Leighton, while Joe is dad to son Harry from a previous relationship.

The Loose Women panellist had her first son Zachary, as a young mother at 17.

Her pregnancy wasn’t planned and she didn’t realise she was pregnant until after the first trimester.

Her second son Leighton was born 4 years later from another relationship.

This post originally appeared on Daily Express :: Celebrity News Feed

6 pregnancy facts that will make you think twice about recent abortion bills

This post has been updated. It was originally published on May 15, 2019.

In May, Texas Governor Greg Abbott signed into law a bill banning abortion after around six weeks of pregnancy—as soon as a fetal heartbeat can be detected. That’s just one of several state laws on the books or in the works that undermine Roe v. Wade, the 1973 Supreme Court decision that deemed “unduly restrictive state regulation of abortion” unconstitutional.

As politicians and higher courts debate the legality of such legislation, much of the discourse around these bills—and, in some cases, their actual wording—reveal multiple misconceptions about, well, conception. Abortion is a topic that triggers strong emotions on all sides, but when it comes to anatomical facts, there’s no room for disagreement. Here’s what you need to know to understand the latest laws.

How easy is it to prevent pregnancy?

No method of contraception is 100 percent effective except for total abstinence. The most effective methods, short of surgical sterilization, are hormonal implants and intrauterine devices (IUDs). Even these devices will fail in some circumstances and no amount of responsibility or diligence excludes a sexually-active person from the risk of pregnancy. (This obviously doesn’t apply to all people, all couples, or all kinds of sexual intercourse.)

Some anti-abortion groups argue that IUDs sometimes work by terminating pregnancies; they can, in rare cases, keep a fertilized egg from attaching to the wall of the uterus. The American College of Obstetricians and Gynecologists refers to fertilization as “the first step in a complex series of events that leads to pregnancy.” For context, around 50 percent of fertilized eggs fail to implant naturally.

When does pregnancy actually start?

Texas’s legislation limits the termination of pregnancy only after six weeks, which means it’s not technically a complete ban. The potential confusion here lies in the way these “weeks” are calculated. Doctors track gestation starting on the first day of their patient’s last normal menstrual period. But conception isn’t actually possible at that time. Conception occurs only in the 12 to 24 hours after ovulation, when the ovary releases an egg, which is usually about 14 days after the first day of the menstrual cycle. So, somewhat confusingly, a person is likely on their second week of “pregnancy” at the moment they become pregnant. This means most pregnant people would have only four weeks after conception to realize they are pregnant (which in and of itself tends to take at least two weeks), decide to seek termination, and abort the pregnancy. This is especially daunting in a state with restrictions like Texas has, where abortions are not covered by insurance, clinics are few and far between enough to sometimes require hours of travel, and a patient must undergo an ultrasound and a 24-hour waiting period before receiving care.

When do pregnancy tests work?

Four weeks might still sound like a long time to make a decision, gather funds, and get to an appointment. But the ability to know you are pregnant does not begin immediately at conception. The most sensitive at-home pregnancy tests are effective four or five days before your next period should start. Menstrual cycles vary, but that means many people will be, as far as a doctor and the law is concerned, about three weeks pregnant by the time a test can reveal their condition, which leaves just three weeks to get a termination. Tests are most reliable after your missed period would have started, at which point you may be four weeks pregnant and have just two weeks to seek an abortion. Before and around this point, false negatives are a possibility.

When do most people realize they’re pregnant?

Many individuals who have no reason to suspect a pregnancy will not think to take a test on the first day of their missed period. Menstrual cycles vary in many people for many reasons, and some methods of birth control can make periods stop entirely. If it is not unusual for your cycle to vary in length by a couple of days, you may find yourself in your fifth week of pregnancy before even realizing your period is late. While some signs of pregnancy can appear during this time, many of those early symptoms are identical to those experienced right before a period—including cramping and light bleeding—which could delay suspicions of pregnancy instead of prompting you to take a test.

When does the fetus’ heart start beating?

Many of the six-week abortion bans are referred to as “heartbeat” bills, with the logic being that fetal heartbeats can be detected as early as six weeks. But the rhythm a doctor can pick up on an ultrasound at that time isn’t a heartbeat, because the embryo has no heart. The embryo is just 3 or 4 millimeters long with no developed organs. Cells are just starting to group together in ways that might eventually grow into hearts and brains. Thanks to the modern-day sensitivity of ultrasound technology, doctors can catch the electrical activity—a rhythmic pulsing—of these cells. But there is no beating heart or even a guarantee that one will develop. Miscarriages up to the eighth week of pregnancy are usually indistinguishable from a heavy period.

What is an ectopic pregnancy?

A bill introduced in Ohio got a lot of attention not because it sought to ban insurance coverage for abortion (as well as birth control that can prevent the implantation of fertilized eggs), but because it included a provision for the coverage of an impossible alternative. State Representative John Becker included an allowance for insurance companies to reimburse patients for “a procedure for an ectopic pregnancy that is intended to reimplant the fertilized ovum into the pregnant woman’s uterus.”

An ectopic pregnancy is one where the fertilized egg implants—and starts growing—somewhere other than the uterus. In 95 percent of cases, the implantation occurs in the fallopian tube, which will rupture within weeks (potentially killing the patient) without the intervention of an abortion. In extremely rare instances the egg can implant somewhere in the abdomen, where there is more room to grow. There have been a handful of surviving babies and mothers under these circumstances, but death for one or both parties is the far likelier outcome: the placenta, which is the organ that provides blood to the growing fetus, can only provide sufficient nourishment by attaching to other organs. The uterus is designed to withstand this; other vital organs are not.

Contrary to the language of Becker’s bill, there is no existing medical procedure that moves a fertilized egg or a growing embryo from one part of the body to another.

Rachel Feltman

Author: empire
This post originally appeared on Science – Popular Science

Marilyn Monroe: Tony Curtis claimed their Some Like It Hot affair resulted in pregnancy

Back in 1958, Billy Wilder shot his classic comedy starring Tony Curtis and Jack Lemmon opposite Marilyn Monroe herself. The movie followed two musicians who disguised themselves in drag to escape the Mafia, after they witnessed the gangsters committing a crime. Monroe, who played singer Sugar, was notoriously difficult on set by often being late or not showing up to filming.

However, it should be noted that Monroe, who would have been 95-years-old today, was also suffering from physical and mental issues at the time.

Curtis, who played saxophone player Joe, famously said that filming romantic scenes with the icon was like “kissing Hitler”

Although years later in 2008, he told The Guardian the origin of this line which seemed to be taken out of context.

He told the outlet: “Someone said to me, ‘Hey, what’s it like kissing Marilyn?’ I said, ‘It’s like kissing Hitler. What are you doing asking me such a stupid question?’ That’s where it came from.”

A year later, Curtis would publish his memoir The Making of Some Like It Hot: My Memories of Marilyn Monroe and the Classic American Movie.

In the book, released just a year before his death, the actor claimed he had an affair with Monroe while both of them were still married.

The pair had briefly dated in 1949 before either of them shot to stardom, but rekindled the romance on the set of Some Like It Hot.

According to The Guardian, the 84-year-old said at the time: “What I experienced with her was unforgettable.”

After filming was completed, Curtis claimed he learned that Monroe had had a miscarriage.

The Hollywood icon would tragically die just a couple of years later on August 4, 1962, of barbiturate poisoning. She was only 36-years-old.

Last year, 2000 Brits were polled by Klook to find out which famous dead star or historical figure they’d most like to meet if time travel were possible.

Monroe, the second American after Elvis Presley, came sixth place. Below is the rest of the Top 10.

1. Princess Diana 8%
2. Freddie Mercury 6%
3. Winston Churchill 6%
4. Elvis Presley 5%
5. William Shakespeare 4%
6. Marilyn Monroe 4%
7. Bob Marley 4%
8. John Lennon 3%
9. Stephen Hawking 3%
10. Robin Williams 3%

This post originally appeared on Daily Express :: Entertainment Feed

Possible link between Tylenol during pregnancy and autism

Possible link between Tylenol during pregnancy and autism

(KXAN) — A new study out of Spain has uncovered what it calls a potential link between pregnant women using the drug acetaminophen — which many people know by the brand name Tylenol — and then their child developing autism or attention-deficit/hyperactivity disorder (ADHD).

Acetaminophen is also commonly known by the name paracetamol. It’s one of the most commonly used pain relievers in the world.

Researchers from the University of Barcelona studied health data from more than 73,000 mother-child pairs across Europe. They found that unborn children exposed to acetaminophen were 19% more likely to be on the autism spectrum and 21% more likely to show signs of ADHD.

“The most consistent pattern of results was observed for the association between prenatal acetaminophen exposure and ADHD symptoms,” the researchers wrote. They said the link was there in both boys and girls but was slightly stronger in boys.

The researchers did warn that this study is just a possible link. Readers should not take their findings as definitive proof.

“Our findings need to be interpreted with caution given the limitations of our study,” the researchers wrote.

Author: Wes Wilson
This post originally appeared on KXAN Austin

Lunar eclipse pregnancy precautions: Can a pregnant woman sleep during an eclipse?

The eclipse will unfold early on Wednesday, May 26, but will not be visible from the UK. Instead, the Moon will enter Earth’s shadow over the Americas, Pacific, Australia and parts of Southeast Asia. When this happens, the Full Moon will take on a red hue and become the beautiful Blood Moon.

Can a pregnant woman sleep during an eclipse?

There is absolutely no scientific rationale behind the myth linking insomnia with lunar eclipses.

Aztecs believed a lunar eclipse was a consequence of a bite being taken out of the Moon.

This idea reportedly translated into the Mexican superstition that if a pregnant woman viewed an eclipse of the Moon, a bite would be taken out of her unborn child’s face.

And even Hindu text credits the eclipse to the head of the demon dubbed Rahu, who devoured the Moon or Sun.

READ MORE: Eclipse LIVE stream: How to watch the Super Flower Blood Moon eclipse

However, another popular myth urges expectant mothers to wear metal and red underwear.

Mexican superstitions say wearing a safety pin, or rather more worryingly, a knife close to her belly, in addition to red underwear, offers protection against their baby being born with a cleft palate.

But while the cause of a cleft palate remains a mystery, there has, of course, been no proven links to eclipses during pregnancy.

Indian astrologers also urge pregnant women to avoid using sharp utensils to slice fruit and vegetables.

They warn this can cause the unborn baby to develop another cleft organ.

Obstetricians gynaecologists believe some pregnant in Pakistan might be told warned to lie straight to prevent a baby from developing crooked joints.

However, Dr Shafia Bhutto told St. Louis Post Dispatch: “There is nothing that will happen to your unborn baby during an eclipse because they are in your uterus.”

And in in India, meanwhile, some expectant mothers are even urged to bathe before and after the eclipse and partake in other religious routines to ward off bad omens associated with the eclipse.

This post originally appeared on Daily Express :: Weird Feed

No, AOC Didn’t Say Pregnancy Lasts 18 Months When Having Twins

In May 2021, shortly after Rep. Alexandria Ocasio-Cortez referred to herself as a Planned Parenthood baby because her mother relied on prenatal care from the organization, a fake quote ostensibly uttered by her about pregnancy lasting 18 months when having twins was recirculated on social media:

This is not a genuine quote from the New York congresswoman. 

This fake quote has been circulating since at least 2018. While we’ve encountered several iterations of this meme, we’ve yet to see anyone note a time or place where this was allegedly said. We have also not been able to find this quote in an news articles, interviews, or through any reputable sources.

Furthermore, this quote has been attributed to other lawmakers.

On memegenerator.com, a website that allows people to make their own memes, this quote was attributed to British politician Diane Abbott. There’s no evidence that Abbott said this either. This quote simply gets falsely attributed to politicians to make it seem as if they are expressing a factually inaccurate statement in order to make them look stupid. (The gestation period for twins is usually shorter at about 36 weeks, compared to 40 weeks for an average pregnancy.)

While fake quotes are often attributed to Ocasio-Cortez in an apparent attempt to make her look stupid, the congresswoman actually has an academic record that some — possibly those who are spreading these memes — may find surprising. While more than a dozen lawmakers do not have college degrees, Ocasio-Cortez is not one of them. The congresswoman graduated cum laude from Boston University in 2011.

Author: Dan Evon
This post originally appeared on Snopes.com