Thyroid cancer: Cushing syndrome is a lesser-known warning sign – what is it?

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Thyroid cancer: Cushing syndrome is a lesser-known warning sign – what is it?

Thyroid cancer is a rare type of cancer affecting the thyroid gland, a small gland at the base of the neck producing hormones. It’s most common in people in their 30s and those over the age of 60. Women are two to three times more likely to develop it than men. Cushing syndrome is a lesser-known warning sign of the disease. What is it?

In a study published in the US National Library of Medicine National Institutes of Health, thyroid carcinoma and Cushing’s syndrome was further investigated.

The study noted: “Two cases of thyroid carcinoma and Cushing’s syndrome are reported.

“Both of our own cases were medullary carcinomas of the thyroid, and on reviewing the histology of five of the other cases all proved to be medullary carcinoma with identifiable amyloid in the stroma.

“A consideration of the temporal relationships of the development of the carcinoma and of Cushing’s syndrome suggested that in the two cases with papillary carcinoma these conditions could have been unrelated, but that in eight of the nine cases with medullary carcinoma there was evidence that thyroid carcinoma was present at the time of diagnosis of Cushing’s syndrome.

“Medullary carcinoma of the thyroid is also probably related to this group of tumours. It is suggested that the great majority of the tumours associated with Cushing’s syndrome are derived from cells of foregut origin which are endocrine in nature.” 


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