Tag Archives: dying

Techland Is Reportedly Bringing Dying Light: Platinum Edition To Switch This October

Dying Light© Techland

Techland will supposedly be bringing Dying Light: Platinum Edition to the Nintendo Switch this October, according to ppe.pl via Nintendo Everything. This version includes all of the DLC from the first game in one “complete” package. All up, that’s four major DLCs and 17 skin bundles.

The survival horror zombie shooter was originally released on PC and multiple other platforms in 2015 and contains co-op play for up to four people. The Switch release will apparently be available in digital and physical form for $ 49.99 USD and hard copies will include a map, survival guide and stickers. Here’s a look:

Dying Light Nintendo Switch

Here’s a general outline, along with an older trailer of the Platinum Edition:

Rove an infected world where only the strongest will make it. Master your combat skills to fight monsters of all kinds, both human and the undead. Parkour through the roofs, craft weapons, and help other survivors while you’re confronting your own nightmares.

Now you can enjoy Dying Light to the fullest with the richest version of the acclaimed open world zombie survival game. Containing four DLCs and seventeen skin bundles, Dying Light: Platinum Edition brings together everything you need to explore all the post-apocalyptic world has to offer. Drive across Harran, as you spread carnage in your buggy, face and survive Bozak’s trials, explore new quarantine zones, and enjoy plenty of new skins and weapons!

Is this a game you would be interested in playing on your Nintendo Switch? Leave a comment down below.

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This post originally posted here Nintendo Life | Latest News

Vital Protective Mechanism Discovered: Dying Cells Protect Their Neighbors To Maintain Tissue Integrity

Artistic rendering of dying cells protecting their neighbors to maintain tissue integrity. Holes in epithelium created by uncoordinated cell death are shown in purple. Credit: © Institut Pasteur / Léo Valon et Romain Levayer

Cells undergoing cell death protect their neighbors to maintain tissue integrity.

To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form, and connectivity. The mechanisms involved in maintaining this integrity remain unknown. Scientists from the Institut Pasteur and the CNRS recently revealed a new process that allows eliminated cells to temporarily protect their neighbors from cell death, thereby maintaining tissue integrity. This protective mechanism is vital, and if disrupted can lead to a temporary loss of connectivity. The scientists observed that when the mechanism is deactivated, the simultaneous elimination of several neighboring cells compromises tissue integrity. This lack of integrity could be responsible for chronic inflammation. The results of the research were published in the journal Developmental Cell on June 2, 2021.

Human epithelia are tissues found in several parts of the body (such as the epidermis and internal mucosa). They are composed of layers of contiguous cells that serve as a physical and chemical barrier. This role is constantly being put to the test by both the outside environment and their own renewal. Tissue renewal involves the formation of new cells by cell division and the elimination of dead cells. The mechanisms that regulate the ability of epithelia to maintain their integrity in contexts involving large numbers of eliminated cells remain poorly understood, despite the fact that this situation occurs regularly during embryogenesis or the maintenance of adult tissues. For example, more than ten billion cells can be eliminated every day in an adult intestine. How are these eliminations orchestrated to maintain tissue integrity and connectivity?

Scientists from the Institut Pasteur and the CNRS set out to identify the mechanisms involved in epithelial integrity and the conditions that can affect epithelial connectivity by using Drosophila (or vinegar flies), an organism studied in the laboratory with a similar epithelial architecture to humans.

Using protein-sensitive fluorescent markers, the research team revealed that when a cell dies, the EGFR-ERK pathway – a cell activation signaling pathway known for its involvement in the regulation of cell survival – is temporarily activated in the neighboring cells. The scientists observed that the activation of the EGFR-ERK pathway protected neighboring cells from cell death for approximately one hour, thereby preventing the simultaneous elimination of a group of cells. “We already knew that this pathway plays a key role in regulating cell survival in epithelial tissue, but we were surprised to observe such protective dynamics between cells,” comments Romain Levayer, Head of the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and last author of the study.

Drosophila Pupa Epithelium

A Drosophila pupa epithelium showing cell contours (gray) and the reporter of the EGFR-ERK pathway (yellow/purple gradient). Credit: © Institut Pasteur / Romain Levayer et Léo Valon

The scientists’ research also shows that inhibiting this protective mechanism has a drastic effect on epithelial tissue: cell elimination becomes random and neighboring cells can be eliminated simultaneously, leading to repeated losses of connectivity. The elimination of groups of neighboring cells is never observed in epithelial tissue in normal conditions, when the EGFR-ERK pathway is not deliberately inhibited, even if a large number of cells are eliminated.

By using a new optogenetic tool that can control cell death in time and space and bypass the protective mechanism, the scientists confirmed that epithelial integrity was compromised when neighboring cells were eliminated simultaneously. “Surprisingly, epithelial tissue is highly sensitive to the spatial distribution of eliminated cells. Although it can withstand the elimination of a large number of cells, epithelial integrity is affected if just three neighboring cells are eliminated simultaneously,” explains Léo Valon, a scientist in the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and first author of the study.

The scientists’ observations confirm that tissues need to develop mechanisms preventing the elimination of neighboring groups of cells. “These observations are important as they illustrate the incredible self-organizing ability of biological tissues, a property that enables them to withstand stressful conditions. So there is no need for a conductor to orchestrate where and when the cells should die; everything is based on highly local communications between neighboring cells,” adds Romain Levayer.

This process seems to have been conserved during evolution. The same protective mechanism based on local EGFR-ERK activation was discovered independently in human cell lines by the research group led by Olivier Pertz at the University of Bern in Switzerland (the results are published in the same journal2). The results of the other study suggest that the protective mechanism is conserved between species separated by hundreds of millions of years, indicating that it is a relatively universal mechanism.

Future research will reveal whether disruption to this cell death coordination mechanism and repeated loss of connectivity in epithelial tissue could be one of the roots of chronic inflammation, a phenomenon responsible for various diseases that are currently among the leading causes of death worldwide.

Distribution of cell deaths in a Drosophila epithelium:

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Development of the Drosophila pupa epithelium showing the location of all cell deaths (colored dots). The cell contours are shown in gray. Credit: © Institut Pasteur / Léo Valon et Romain Levayer

Activation of the EGFR-ERK pathway in neighboring cells:

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Activation of the EGFR-ERK pathway in the neighbors of a cell extruded from the tissue. The reporter on the left is excluded from the nucleus when the pathway is activated (the eliminated cell is circled in green). Activation can also be viewed by other pathway sensors (the FRET sensor – red for strong activation. Credit: © Institut Pasteur / Romain Levayer et Léo Valon

References:

  1. “Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination” by Léo Valon, Anđela Davidović, Florence Levillayer, Alexis Villars, Mathilde Chouly, Fabiana Cerqueira-Campos and Romain Levayer, 2 June 2021, Developmental Cell.
    DOI: 10.1016/j.devcel.2021.05.006
  2. “Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival” by Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, Coralie Dessauges, Pascal Ender, Yannick Blum, Robert M. Hughes, Andrew R. Cohen and Olivier Pertz, 2 June 2021, Developmental Cell.
    DOI: 10.1016/j.devcel.2021.05.007

This research project was supported by the European Research Council (ERC), a Marie Skłodowska-Curie post-doctoral fellowship, the Fondation pour la Recherche Médicale (FRM) et the Cercle Fondation Schlumberger pour l’Education et la Recherche (FSER), R.Levayer 2019 laureate.

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This post originally posted here The European Times News

Parking tickets are ‘terrorising’ business owners in ‘dying’ town centre

The companies have been hit with charges after failing to follow confusing rules around loading and unloading goods. Businesses are able to load and unload before 10:30 am and after 4:30 pm on the busy Newmarket Street.

“It’s common sense when people are parked outside their businesses, it’s the only way they can operate.”

Zoe Hunter, co-owner of food business They Bake has also been hit with penalties for unloading stock.

She said they had asked how to get a permit but the attendant did not help.

Ms Hunter said businesses have been “a bit shocked” because many had suddenly started receiving tickets.

The permit states drivers must not be used during the day between 10:30 am and 4:30 pm.

Drivers can apply for a permit by contacting South Ayrshire Council Customer Services team.

Speaking to the Daily Express, the ARA said a public consultation will soon be launched to look at parking in the area.

They said: “The current rules for the use of loading bays on High Street, Ayr are very clear and are enforced to ensure that drivers comply with the rules and that the bays can be used appropriately.

“The loading bays are for the use of goods vehicles that are loading/ unloading items or for the delivery or collection of goods from nearby premises.

“The loading bays can be used in this manner for up to 30 minutes so long as there is evidence of loading or unloading taking place.

“Ayrshire Roads Alliance parking attendants are not ‘terrorising’ residents, they are doing the job that they are employed and instructed to do.

“Parking attendants, like all employees, have a right to work without fear of violence or verbal abuse. The Alliance will continue to take action, where appropriate, to protect our employees.

“South Ayrshire Council is currently holding a public consultation exercise that outlines a range of proposals for parking in Ayr and any decisions taken by the Council will be fully implemented by the Ayrshire Roads Alliance.”

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This post originally posted here Daily Express :: Life and Style
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Prince Charles to refuse one of Philip’s dying wishes

Prince Charles will reportedly stop brother Edward becoming Duke of Edinburgh.

But the move from the Prince of Wales comes despite his dad Prince Philip’s wishes for when he died.

The Duke of Edinburgh is a title which can be passed from royal to royal.

READ MORE Prisoner’s girlfriend funded lavish lifestyle as she ran his drug empire – and even got mum dealing

And the former Duke of Edinburgh, who died aged 99 in April before being buried at St George’s Chapel, at Windsor Castle, in front of 30 mourners, wanted his son Edward to take on the title in the event of his death.

But Charles is ready to block the move – because he wishes as future King to have a “slimmer monarchy”.

Edward mourned at the funeral alongside wife, Sophie, while Charles also attended, alongside Camilla, the Duchess of Cornwall.

A source close to Charles said: “The Prince is the Duke of Edinburgh as it stands, and it is up to him what happens to the title. It will not go to Edward.”

“It isn’t just about whether Edward becomes Duke of Edinburgh by rite of passage or not, there have been discussions about the whole top tier of the Royal Family,” a source told the Daily Mail.

A royal aide told the newspaper: “It was probably human nature to transfer your affection to the youngest, who in the scheme of things will inherit nothing. It was why he wished Edward to have his title.”

“Put yourself in his shoes,” the aide told the Mail. “You have been consort and then [Charles] comes along and is suddenly the heir.”

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This post originally posted here United Kingdom News

‘Dying in their homes’: COVID-hit Indonesians scramble for oxygen

Jakarta/Bekasi, Indonesia – Outside a small store in South Jakarta, dozens of people line up for the chance to save the life of their loved one.

In the Indonesian capital, oxygen is an increasingly precious commodity as the country battles a relentless surge in cases of COVID-19.

“I’m here to buy an oxygen tank for my mother, she tested positive on Sunday and we tried several hospitals but all are full,” Pinta said, as she waited in line.

“I received a list of places that sell oxygen but every single one that we went to was closed or ran out. Thank God, my friend told me to come here.”

Searching for oxygen in Jakarta in recent weeks is an unpredictable scramble – a sick person’s chances of survival can come totally down to chance, depending on whether their relative was at the right store, at the right time.

Another woman in line, Winda, says she is trying to find oxygen for her brother-in-law.

“I had trouble finding oxygen last night. I went to five places, including this store and a big medicine market but all ran out,” she said.

“We went to the health centre … they said to give oxygen at home while waiting for the hospital … but we have been waiting for two days and there’s no hospital referral.”

‘We are more worried than ever’

Twenty-nine-year-old Minanti is caring for her elderly father at home after she tried and failed to get him admitted to hospital.

COVID-hit Indonesians scramble for oxygenMinanti is one of many Indonesians forced to care for the sick at home. Her father has underlying conditions that make him particularly vulnerable to COVID-19 [Al Jazeera]

He is diabetic, and has heart and kidney problems, too, putting him at increased risk from coronavirus.

But he still could not get a place in Jakarta’s crowded hospitals.

“We tried hospitals near our home … we went to the emergency unit and they said, ‘look around, it is full,’ and they told us even they have problems with oxygen,” Minanti said.

“Another hospital was also full. They have a tent in front of the building, full of sick people … we felt so scared.”

Now, like thousands of Indonesians, Minanti understands the struggle of trying to procure an oxygen cylinder during this wave of infections.

“It was super difficult to get the oxygen tank. We borrowed it and suddenly, the owner asked for it back because they, too, got COVID,” she said.

Eventually, she was able to buy an oxygen tank – but refilling it is a constant struggle.

“It was almost like a miracle to get the tank. Now, he has to have oxygen nonstop because he is constantly out of breath,” she said.

“The government should have responded fast from the beginning … now, cases have exploded. The oxygen tank is difficult to buy, and it’s difficult to refill and the hospitals are already full.”

‘We could not help them’

Workers from a public health clinic check on patients of COVID-19 who are isolating at home [Fakhrur Rozi/Al Jazeera]

It is not only the general populace struggling with shortages of oxygen and medication – health professionals also told Al Jazeera they do not have enough essentials to help everyone in need.

Dr Erni Herdiani is the head of the Lemah Abang Health Clinic in Bekasi, on the outskirts of Jakarta.

“We need oxygen tanks, oxygen refill and medication. We treat severe conditions, we need medication like remdesivir and we cannot find it,” she said.

“We need to give the patients oxygen and medication. We are lacking oxygen tanks … this is beyond my expectation. So many patients need oxygen and the refilling lately is even harder.”

Dr Erni would like to buy more oxygen tanks for her clinic but says it is impossible.

“Right now, we just cannot buy it. There are no tanks. We need the government to provide it,” she said.

As hospitals in Java and other parts of Indonesia edge closer to full capacity, it is up to public health clinics to look after some of the thousands of sick people who cannot be admitted.

Dr Erni Herdiani heads a health clinic on the outskirts of Jakarta and says it’s increasingly difficult to find the oxygen tanks, refills and medications that need to treat patients with COVID-19 [Jessica Washington/Al Jazeera]

But Dr Erni’s team is also under pressure – there are fewer than 30 health workers at her clinic and they are monitoring more than 300 patients.

Every day, a team of roving medics from her clinic visit some of the sick.

The team has become accustomed to finding patients dead in their homes.

“Right now, there is a lot of loss [of life] at home. Sometimes, we have the report of someone who died, when we check the body, they are positive,” she said.

Dr Erni believes the official government figures, which put the death toll at more than 66,000, are an underestimate.

“It’s underreported. It is very sad because we could not help them.”

Even major hospitals are grappling with shortages or delays in receiving oxygen.

This week, at least 33 patients with severe coronavirus infections died in hospital in the city of Jogjakarta, on the island of Java, when the hospital temporarily ran out of oxygen.

A spokesperson at Dr Sardjito General Hospital told the media there had been delays from suppliers.

‘We don’t see that issue’

Dr Siti Nadia Tarmizi from the Indonesian Ministry of Health said they have already rectified logistical issues in transporting oxygen.

“What happened in Jogjakarta … because of the number of patients, their stock was running out very fast and the next shipment was only the following morning. They had limited oxygen … time was lacking there,” she said.

“We are speeding up the distribution. Previously, it was two or three days, now we are asking [them] to be ready to send within a 12- to 24-hour cycle.”

Healthcare workers check the oxygen tanks inside an emergency tent for patients under observation for COVID-19 at a hospital in Bekasi near Jakarta [File: Mast Irham/EPA]

The health minister has instructed oxygen producers to redirect their efforts towards providing medical rather than industrial oxygen.

“We are working on managing the oxygen situation, in fact from our national gas industry, the capacity is still there,” Dr Nadia told Al Jazeera.

Dr Nadia said the priority is to provide oxygen for hospitals and public health facilities. She said there is no oxygen shortage.

“I don’t think that has happened. We currently don’t see that issue for health facilities, they have low numbers but we try to fill up their stock,” she said.

“Cases might increase to 50,000 or 70,000 a day. The need [for oxygen] is fulfilled but it is not at the safe level yet.”

Dr Nadia says the Ministry of Health did not anticipate such a big jump in cases.

“The main problem was, last week, we had a huge number of patients which we did not expect,” she said.

“It is very difficult to find ambulance and health facilities. Sometimes, when reaching the health facility, they already died on the way … or patients are dying in their homes.”

Get a Closer Look at the Monsters in Dying Light 2 Stay Human

The night has come in our new gameplay video, so grab your flashlight and join us, as we explore the secrets of a dark zone. Take a closer look at various types of the Infected, stand face to face with a Volatile, and try to make it through in one piece. But that’ll only be possible if you check out our hints. Are you ready?

One thing is to know your enemies. Another, to know their weaknesses. We’ll cover both, just to be sure. So, who are all the monsters you’ll meet in The City? Let’s say you’d get infected. First, you might think it’s just the flu, as the symptoms are very similar. That is, if you didn’t live in a post-apocalyptic city overrun by a deadly virus, where you’d know just too well it’s more than that, and your race against the infection would begin.

You’d most likely also have a biomarker — a special wristband showing the stages of your sickness and how close you’re to the turning point. If you failed to find enough UV light or Antizin in time, the symptoms would get worse and worse, until you wouldn’t even be able to speak anymore. Then, your biomarker would turn red, and it’d be a straight road to becoming a Volatile. And once you’ve turned, there’s no going back.

After reaching the turning point, the thing that you wanted the most — UV rays — becomes your worst enemy. Stay in the sun, and you’ll degrade into a wreck of a monster, a Biter. You’ll lose whatever leftovers of consciousness you might’ve had and keep roaming the streets mindlessly until you die from the light.

But it doesn’t have to get that bad, though it’s rather relative, because if you let the virus progress in the dark, you’ll become the strongest monster of all — a Volatile. Fast, intelligent, and deadly, he’s the one thing you’d never want to meet. So, our first tip should be quite clear by now — stay in UV light and use it against the monsters. It’ll keep you safe from both the infection and the Infected.

But exposure to light is only one factor that defines which monster you’ll become. There are more, like the chemicals dropped onto The City in the past. Accelerating the progression of the virus in the sick individuals, they caused their bodies to change too rapidly, which, in turn, led to various mutations.

For example, if the virus seized somebody’s vocal cords, they could become a Howler, an Infected who is both too afraid and unable to fight a human, so he calls and alerts those more fit for the job with his piercing scream. Don’t let him spot you. Another product of the chemicals is the Demolisher, whose body grew extremely large, especially the hands, and his skin hardened with stonelike tissue. He can charge or slam the ground with his fists to create a kind of a shockwave as well as throw immensely heavy objects, so watch out for those flying boulders. Against the Demolisher, you will need to rely on your agility.

But there’s also the Banshee — smaller, yet so deft you won’t see her coming. She’s quick and takes you by surprise, attacking you from the roofs. If you get to fight her, your strength will be your best chance. And then, some monsters mutated in the most unpredictable ways.

The Revenant got a curious ability to buff and summon nearby Infected with the substance coming from the growths on his back. He’s rather uncommon. You’ll find him only in specific places, and only at night. But we’re not so sure looking for him is such a good idea. Unless you’re ready to fight an army.

So the next tip would be to never ever enter the chemical clouds in The City, and when you fight those who did, adjust your tactics to abuse their weaknesses. And since we’re at the “no entry” kind of advice, this one should follow naturally: Don’t roam the dark zones during the day. That’s when all the Infected are there, hiding from the sun. It’s smart to use that time to explore the streets and come back to the dark zones at dusk, when they have left to hunt. It doesn’t mean you can be careless, though, as there are still some monsters, Volatiles even, lying and walking around. That’s when our improved stealth mechanics come in handy. Don’t rush and think about your next steps, and you’ll make it through without having a horde of the Infected chase you.

And it’s worth trying your luck in the dark zones, however dangerous they may be. They’re full of valuable loot, inhibitors probably being the most precious of all. Now, these chemicals are the ones you actually want. They’ll boost your skills, allowing you to fight better, jump higher and run faster than any other human. But it has a darker side too. You’ll have to find out for yourself, should you manage to survive long enough.

Until then, we’re going to keep showing you more elements of the world of Dying Light 2 Stay Human, with parkour and combat hints coming soon. If you still think it’s only a matter of time before you turn, why not get an early glimpse at what you might become? Answer the questions at dyinglightgame.com/whichmonster and we’ll tell you what future awaits you in The City. Will you stay human?

Xbox LiveXbox Live

Dying Light 2

Techland

Upgrade your experience with Smart Delivery. Buy the game once to both play it on Xbox One and get its optimized version for Xbox Series X | S

Pre-order the Standard Edition now to get the exclusive items:
– “Reload” outfit
– “Reload” weapon skin
– “Reload” paraglider skin

Over twenty years ago in Harran, we fought the virus—and lost. Now, we’re losing again. The City, one of the last large human settlements, is torn by conflict. Civilization has fallen back into the Dark Ages. And yet, we still have hope.

You are a wanderer with the power to change the fate of The City. But your exceptional abilities come at a price. Haunted by memories you cannot decipher, you set out to learn the truth… and find yourself in a combat zone. Hone your skills, as to defeat your enemies and make allies, you’ll need both fists and wits. Unravel the dark secrets behind the wielders of power, choose sides and decide your destiny. But wherever your actions take you, there’s one thing you can never forget—stay human.

VAST OPEN WORLD
Participate in the life of a city engulfed in a new dark era. Discover different paths and hidden passages, as you explore its multiple levels and locations.

CREATIVE & BRUTAL COMBAT
Take advantage of your parkour skills to tip the scales of even the most brutal encounter. Clever thinking, traps and creative weapons will be your best friends.

DAY AND NIGHT CYCLE
Wait for night to venture into dark hideouts of the Infected. Sunlight keeps them at bay, but once it’s gone, monsters begin the hunt, leaving their lairs free to explore.

CHOICES & CONSEQUENCES
Shape the future of The City with your actions and watch how it changes. Determine the balance of power by making choices in a growing conflict and forge your own experience.

2-4 PLAYER CO-OP GAMEPLAY
Play in up to four-player co-op. Host your own games or join others and see how their choices have played out differently than yours.

Author: Marta Szczechowska, Writer, Techland
Read more here >>> Xbox Wire

Life after death: Dying woman felt 'pulled into the light' where she felt peace and joy

The jury is still out on whether life goes on after physical death but many people claim to already known an answer. People who have gone through so-called near-death experiences (NDEs) frequently describe visions and sensations of what they believe is the afterlife. One such person is a woman named Leila, who claims to have temporarily passed into the afterlife more than 15 years ago.

Leila shared the account of her NDE with the Near-Death Experience Research Foundation (NDERF), explaining how she was dying in hospital from complete liver failure.

She recalled saying goodbye to her closest family while a pastor said one final prayer for her.

When everyone left, she closed her eyes and drifted away, praying to God “to please help me”.

Leila said: “Next, I was above my body. I knew that I was dead.

READ MORE: Life after death: THIS is the process you will go through when you die

“It was dark in the room, but I could see light. I was fearful at first, but the closer I got to the light, my feelings started changing.

“All fear and negativity disappeared. I did not walk into the light, yet it felt like I was being pulled into it; it was like being slowly sucked into the light.”

According to Leila, the light was incredibly bright but it did not blind or hurt her eyes.

She said it was brighter than looking at the Sun but it felt soft and comfortable.

When she reached the brightest point of the light she was no longer moving.

Leila was then overcome with a feeling of peace, calmness and joy.

She said: “In that moment, my experience was orders of magnitude better than any kind of earthly experience.

“For instance, I consider a mother’s joy and love felt from the birth of her child is the best earthly feeling.

“But this experience makes that appear like a drop of water compared to a vast sea or ocean of this experience. There was no other place I wanted to be.”

In a bizarre twist of events, Leila said she could see a “white, shadowy, female figure” in the light.

A voice heard inside of her head then told her to “go back”.

She believes the shadowy figure was her dead grandmother who raised her as a child.

Leila said: “She didn’t say why, but I knew it was because my work on Earth wasn’t done. My children needed me.”

The next things she knew, she had woken up back in her body in the hospital, gasping for air.

Although the account is truly incredible, there is very little medical evidence to suggest it was genuinely paranormal or supernatural.

Instead, researchers have found some evidence to suggest the NDEs might be hallucinations caused by brain activity even when the heart stops.

A study at the University of Michigan has analysed brain activity in rats with clinically induced cardiac arrest.

According to Dr Jimo Borjigin, associate professor of molecular and integrative physiology and associate professor of neurology, the study found activity in the rat brains, which may even translate to human NDEs.

He said: “The prediction that we would find some signs of conscious activity in the brain during cardiac arrest was confirmed with the data.”

Other researchers have proposed NDEs are hallucinations triggered by a lack of oxygen flowing to the brain during a moment of trauma or cardiac arrest.

Author:
This post originally appeared on Daily Express :: Weird Feed

Coral reefs are dying, but it’s not too late to save them

The global outlook for coral doesn’t look good. The reef-building animals, which create the living architecture for some of the most diverse ecosystems on the planet, are acutely vulnerable to climate change, and are experiencing heavy losses already. Without dramatic emissions reductions in the coming decade, their future is increasingly dire.

But that doesn’t mean that the end is inevitable. As two recent studies make clear, humans can still help reefs hang on in a warming ocean.

“We really do think of our story as good news,” says Mary Donovan, a professor of conservation science at Arizona State University, and a lead author on one of the studies. “The impacts of climate change on coral reefs are quite overwhelming. So to be able to uncover other effects [on reefs] puts it in the hands of everybody—we’re saying, human impacts are making things worse, and also, we can actually improve conditions.”

The primary climactic threat to coral is called bleaching. Coral polyps, the animals that build the reef structure itself, live in a symbiotic partnership with colorful algae, which provide food. But in marine heat waves, the polyps kick out their algae partners, leaving the reef bone-white. A healthy reef can recover from the blow, but if conditions get bad enough, it will die entirely, and the entire structure will begin to crumble.

According to Donovan’s research, published last week in Science, those bleaching events could be exacerbated by two key local trends: pollution and overfishing. And that means that local restoration efforts could help reefs survive the majority of heat waves.

The reefs that fared the worst after bleaching events tended to have an overabundance of seaweed, which flourishes in water polluted with nutrient-rich runoff, and which would normally be kept in check by herbivorous reef fish. That seaweed releases chemicals that directly stress the reef.

“When it gets really hot, coral gets really stressed,” Donovan says, “and if you’ve got anything else stressing them out, that’s really bad.”

More surprisingly, bleaching was also associated with an overabundance of sea urchins. Under normal circumstances, those urchins would feed on the seaweed. But when their predators are overfished, the urchin population can also explode.

“There’s kind of this Goldilocks zone, where at very extreme abundances, they’re doing more harm than good,” Donovan says. “There’s nothing left to eat, there’s so many of them, they’ve chowed away at the bottom, so they just keep going. They’ve got these really strong teeth, for lack of a better word, and they start eroding away the reef itself.”

Humans can also help undo that damage.

For one thing, local fishery managers might protect the species—parrotfish, surgeonfish, unicorn fish—that go after seaweed. That’s already happening in Hawai’i’s Kahekili Marine Reserve, Donavan says. But, she stressed, “in many of the places where coral reefs exist, people living near the reefs and the reefs themselves are highly connected. Often the society is relying very heavily on the reef for subsistence. It’s important not to paint fishing as a bad thing. It’s a matter of survival for a lot of people all over the world.”

[Related: How divers found 4 new coral species, hidden in plain sight]

More obviously, reducing nutrient pollution (often by cleaning up sewage), could both help reefs and human health.

Other research, published in the Proceedings of the National Academy of Sciences, suggests that humans might also be able to nudge the evolution of corals towards bleach-resistance.

In the Caribbean and Great Barrier Reef, conservationists have already begun planting tens of thousands of corals from nurseries. Ideally, they would select the corals that appeared to survive heat waves without bleaching. But that requires bleach-resistance to be a trait that survives when a coral is moved. It’s possible those corals were resilient because of their habitat, or would be so stressed by the move that they’d be newly vulnerable.

To test how bleach resistance travels, a team in Hawai’i took pieces from corals that had weathered back-to-back heat waves, and moved them around the reef.

It took several months for them to become settled in their new environments, but after that, both appeared to keep their heat-resistant properties in lab tests. And because a coral is home to thousands of genetically identical organisms, it’s likely that as the transplant grows, it will make the entire section of reef more heat tolerant.

Taken together, the two studies outline a multifaceted approach to saving coral.

“Many of the people who are most impacted by the decline of corals are not the ones in control of climate policies,” Donovan says. And headlines about massive bleaching events, like on the Great Barrier Reef in 2015 “leave a lot of people discouraged. So our work clearly sends the message that action on all levels is necessary in ensuring the future of corals.”

Philip Kiefer

Author: Sara Chodosh
This post originally appeared on Science – Popular Science

Dying Light 2 Stay Human Pre-Orders Available Now

The night is coming, survivors! Starting today, you can reserve your copy of Dying Light 2 Stay Human and get your hands on some sweet extras while you’re at it. Every player who pre-orders the game will get a unique outfit, a weapon skin and a paraglider skin — way to make an entrance into The City!

Dying Light 2 Stay Human will take you over twenty years after humanity lost its fight to the virus in Harran, which is now but a memorial of sacrifice and defeat. Now, mankind has found refuge in The City — one of the last few human settlements on Earth. Civilization has fallen back into the Dark Ages, and everything you took for granted is no more. But in the remnants of the past, a new order emerges and an extremely fragile balance of power is in your hands.

Dying Light 2

Now that you get the gist of it, let’s get to what exactly we think it is that you’ll love about Dying Light 2 Stay Human — beginning with our favourite two words: vertical freedom. We wanted to make your parkour experience feel intuitive, natural and, above all, fun. Since The City is all about its multiple levels and both their unique challenges and assets that you can turn to your advantage, we’ve made sure you’d be able to move through it smoothly. You get numerous parkour skills to explore, combine and choose from along an improved grappling hook and a paraglider — all you need to make the vast open world of Dying Light 2 Stay Human your oyster.

Pretty cool, right? But roaming through the map is not the only way to use parkour abilities. They also play a major role in combat, allowing you to surprise your enemies with your insane agility. Fights might turn brutal and tough, so you need to be smart, creative and unpredictable. You can think of the world as a playground, where you experiment with various tactics, weapons, approaches and elements of the environment. We ensured there’s always more than one way to get an edge over your opponent.

Dying Light 2

All right, we know what you’re thinking now, “What’s going on with The City? Doesn’t it have a name?” And in fact, it did have one: Villedor. It used to be a cradle of culture, humming with life, full of travellers from all over the world. But the virus and consequent fall of civilisation brought all of that to a standstill. Over time, people started to believe Villedor to be the last haven of civilization, renaming it The City; and although some new settlements were established since then, it remains the icon of hope and survival.

But history lessons aside, let’s focus on the present. Dying Light 2 takes place in a new era, called Modern Dark Ages, which is basically the Dark Ages, only if it happened today. People reject science, medieval structures rise next to ruined shopping malls and desolate office buildings. Lettuce grows on the roofs. No, we’re not kidding. It really does, hear us out. As the infection has become more sensitive to UV rays, society ekes out an existence in the safety of sunlight, while the Infected lurk in the shadows. The streets have become too dangerous to roam, so in a desperate attempt to survive, people fled to the rooftops, building makeshift houses and farms there. They may go down to the ground level by day, as sunlight herds the Infected into the buildings, but nightfall shifts the balance completely. Beasts leave their liars and the hunted become hunters. Most folk cower in hubs, hoping their UV lamps will keep them safe, but for you, this is a chance to explore places no one else dares enter and take the spoils.

Dying Light 2

Plenty of people from various cultures and places closed in a city that’s in a state of permanent siege — you couldn’t possibly think there’d be no conflicts. Law and order versus power of friendship, none of them perfect, none flawless. Both trying to make through. Depending on which faction you help, The City will react with changes in its appearance, threats and atmosphere. You steer its future, so steer wisely, as consequences will follow.

Whether it’s the choices concerning your playstyle or ones that’ll decide the future of The City, we wanted you to feel that they really matter. The former will determine your weaknesses and strengths in combat, your preferred approach and tactics. The latter — your relationships, interactions and surroundings. By choosing sides, making moral decisions, and testing different options and paths, you can explore multiple scenarios and unravel various outcomes. And if you’re curious and can’t wait to see how other choices might play out, remember Dying Light 2 Stay Human has a co-op mode, where you can join your friends in their games and see for yourself. Or they can join you and marvel at the grandeur of your achievements.

Stay tuned for more news regarding Dying Light 2 Stay Human and remember — no one’s ever regretted getting free skins.

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Dying Light 2

Techland

Upgrade your experience with Smart Delivery. Buy the game once to both play it on Xbox One and get its optimized version for Xbox Series X | S Pre-order the Standard Edition now to get the exclusive items: – “Reload” outfit – “Reload” weapon skin – “Reload” paraglider skin Over twenty years ago in Harran, we fought the virus—and lost. Now, we’re losing again. The City, one of the last large human settlements, is torn by conflict. Civilization has fallen back into the Dark Ages. And yet, we still have hope. You are a wanderer with the power to change the fate of The City. But your exceptional abilities come at a price. Haunted by memories you cannot decipher, you set out to learn the truth… and find yourself in a combat zone. Hone your skills, as to defeat your enemies and make allies, you’ll need both fists and wits. Unravel the dark secrets behind the wielders of power, choose sides and decide your destiny. But wherever your actions take you, there’s one thing you can never forget—stay human. VAST OPEN WORLD Participate in the life of a city engulfed in a new dark era. Discover different paths and hidden passages, as you explore its multiple levels and locations. CREATIVE & BRUTAL COMBAT Take advantage of your parkour skills to tip the scales of even the most brutal encounter. Clever thinking, traps and creative weapons will be your best friends. DAY AND NIGHT CYCLE Wait for night to venture into dark hideouts of the Infected. Sunlight keeps them at bay, but once it’s gone, monsters begin the hunt, leaving their lairs free to explore. CHOICES & CONSEQUENCES Shape the future of The City with your actions and watch how it changes. Determine the balance of power by making choices in a growing conflict and forge your own experience. 2-4 PLAYER CO-OP GAMEPLAY Play in up to four-player co-op. Host your own games or join others and see how their choices have played out differently than yours.

Author: Marta Szczechowska, Writer, Techland
This post originally appeared on Xbox Wire

Richard Madeley talks mum's dying wish in last conversation amid dementia and cancer fight

“And she nodded and said, ‘That’s right, yes, yes, yes, of course, yes. Oh good’, she said, ‘It’ll be fine now.’ 

“And she sort of slipped back to sleep and that was it, that was kind of the last conversation.”

He added: “Although she couldn’t remember her mother, she could remember her very simple Christian faith, which sadly I don’t share. And it was great that she still had that comfort when when she went.”

The Dementia Hero Awards’ virtual ceremony will take place tomorrow at 7pm during Dementia Action Week 2021.

Alongside Richard’s appearance as host, the awards will also be presented by Society Ambassadors Angela Rippon CBE, Carey Mulligan and Sir Tony Robinson and our supporters Judy Finnigan and Anne-Marie Duff.

To sign the petition to #CureTheCareSystem and support Dementia Action Week (17-23 May 2021) visit alzheimers.org.uk/DAW. And for information, advice and support call Alzheimer’s Society Dementia Connect support line (0333 150 345) or visit our website.

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This post originally appeared on Daily Express :: Celebrity News Feed